Submillimeter-scale surface gradients of immobilized protein ligands

We describe a method to produce antibody-captured ligand gradients over biologically relevant distances (hundreds of micrometers) whereby the ligand density and gradient shape may be tailored. Separation of the ligand from the solid-phase surface ensures that the biological activity of the ligand re...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1991. - 25(2009), 8 vom: 21. Apr., Seite 4243-6
1. Verfasser: Walker, Robert A (VerfasserIn)
Weitere Verfasser: Cunliffe, Vincent T, Whittle, Jason D, Steele, David A, Short, Robert D
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Acrylates Antibodies Biocompatible Materials Calcium-Binding Proteins Carbodiimides DLK1 protein, human Fluorescent Dyes Intercellular Signaling Peptides and Proteins mehr... Ligands Membrane Proteins Proteins acrylic acid J94PBK7X8S