Conditional protein stabilization via the small molecules Shld-1 and rapamycin increases the signal-to-noise ratio with tet-inducible gene expression

Cellular mechanisms control one or more of the three basic levels of regulation (transcription, translation, and protein activity/locality), allowing for finely tuned spatial and temporal regulation of protein expression patterns. Gene regulation constructs in wide use today often employ a constitut...

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Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1988. - 46(2009), 1 vom: 21. Jan., Seite 44-50
1. Verfasser: Almogy, Gal (VerfasserIn)
Weitere Verfasser: Nolan, Garry P
Format: Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Morpholines Recombinant Fusion Proteins Repressor Proteins Shield-1 compound Trans-Activators enhanced green fluorescent protein tetracycline resistance-encoding transposon repressor protein mehr... Green Fluorescent Proteins 147336-22-9 Doxycycline N12000U13O Sirolimus W36ZG6FT64