Therapeutic injection of C-class CpG ODN in draining lymph node area induces potent activation of immune cells and rejection of established breast cancer in mice
In order to develop novel CpG ODNs for the treatment of breast cancer, we have designed a series of CpG ODNs and evaluated their anti-tumor activity in a breast cancer mouse model. Interestingly, a C-class CpG ODN, designated as YW002, showed a vigorous activity on the inhibition of tumor growth in...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 3 vom: 01. Juni, Seite 426-37
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| 1. Verfasser: |
Yang, Liang
(VerfasserIn) |
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| Weitere Verfasser: |
Sun, Luguo,
Wu, Xiuli,
Wang, Li,
Wei, Hongfei,
Wan, Min,
Zhang, Peiyin,
Yu, Yongli,
Wang, Liying |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2009
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Adjuvants, Immunologic
CPG-oligonucleotide
Oligodeoxyribonucleotides |
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