Accessory cell dependent NK cell mediated PBMC IFN-gamma production is defective in HIV infection

Accessory cell dependent NK cell mediated PBMC IFN-gamma production is defective in HIV infection

HCV and HIV infections impair dendritic cell function. We evaluated the impact of HCV, HIV, and HCV-HIV infection on MDC-NK interactions by analyzing CD3 depleted PBMC for NK cell IFN-gamma in response to IL-12 or poly (I:C). Purified MDC and NK cells were analyzed for TLR ligand-dependent, MDC-depe...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 2 vom: 15. Mai, Seite 288-97
1. Verfasser: Yonkers, Nicole L (VerfasserIn)
Weitere Verfasser: Milkovich, Kimberly A, Rodriguez, Benigno, Post, Anthony B, Asaad, Robert, Heinzel, Frederick P, Valdez, Hernan, Tary-Lehmann, Magdalena, Anthony, Donald D
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Antiviral Agents Hepatitis C Antibodies Interleukin-12 187348-17-0 Interferon-gamma 82115-62-6 mehr... Granzymes EC 3.4.21.- Poly I-C O84C90HH2L
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