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231223s2009 xx |||||o 00| ||eng c |
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|a 10.1021/la8035659
|2 doi
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|a pubmed25n0620.xml
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|a (NLM)19161273
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|a DE-627
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|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Tzokova, Nadia
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Soft hydrogels from nanotubes of poly(ethylene oxide)-tetraphenylalanine conjugates prepared by click chemistry
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|c 2009
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 31.03.2009
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|a Date Revised 01.12.2018
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|a published: Print
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|a Citation Status MEDLINE
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|a A new poly(ethylene oxide)-tetraphenylalanine polymer-peptide conjugate has been prepared via a "click" reaction between an alkyne-modified peptide and an azide-terminated PEO oligomer. Self-assembled nanotubes are formed after dialysis of a THF solution of this polymer-peptide conjugate against water. The structure of these nanotubes has been probed by circular dichroism, IR, TEM, and SAXS. From these data, it is apparent that self-assembly involves the formation of antiparallel beta-sheets and pi-pi-stacking. Nanotubes are formed at concentrations between 2 and 10 mg mL(-1). Entanglement between adjacent nanotubes occurs at higher concentrations, resulting in the formation of soft hydrogels. Gel strength increases at higher polymer-peptide conjugate concentration, as expected
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|a Journal Article
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|a Hydrogels
|2 NLM
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|a Polyethylene Glycols
|2 NLM
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7 |
|a 3WJQ0SDW1A
|2 NLM
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| 650 |
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|a Phenylalanine
|2 NLM
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| 650 |
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7 |
|a 47E5O17Y3R
|2 NLM
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| 700 |
1 |
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|a Fernyhough, Christine M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Topham, Paul D
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sandon, Nicolas
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Adams, Dave J
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Butler, Michael F
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Armes, Steven P
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ryan, Anthony J
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1985
|g 25(2009), 4 vom: 17. Feb., Seite 2479-85
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnas
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| 773 |
1 |
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|g volume:25
|g year:2009
|g number:4
|g day:17
|g month:02
|g pages:2479-85
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|u http://dx.doi.org/10.1021/la8035659
|3 Volltext
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