CD4(+)CD25(+)CD127(low/-) regulatory T cells express Foxp3 and suppress effector T cell proliferation and contribute to gastric cancers progression

Increased populations of regulatory T cells (Tregs) impair anti-tumor immunity. Recently, the transcription factor Foxp3 has been reported to play a key role in CD4(+)CD25(+) regulatory T cell function and represents a specific marker for these cells. However, Foxp3 is a nuclear protein and is of li...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 1 vom: 01. Apr., Seite 109-18
1. Verfasser:	Shen, Li-Song (VerfasserIn)
Weitere Verfasser:	Wang, Jian, Shen, Ding-Feng, Yuan, Xiang-Liang, Dong, Ping, Li, Mei-Xing, Xue, Jian, Zhang, Feng-Min, Ge, Hai-Liang, Xu, Dakang
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2009
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Biomarkers FOXP3 protein, human Forkhead Transcription Factors Interleukin-2 Receptor alpha Subunit Interleukin-7 Receptor alpha Subunit