Aspirin and salicylates modulate IgE-mediated leukotriene secretion in mast cells through a dihydropyridine receptor-mediated Ca(2+) influx

Aspirin is a well-known nonsteroidal anti-inflammatory drug (NSAID) that may potentiate some acute allergies and causes adverse immunological reactions collectively referred to as aspirin intolerance. Aspirin intolerance is accompanied by increased leukotriene (LT) synthesis, and high levels of seru...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 1 vom: 03. Apr., Seite 145-56
1. Verfasser:	Togo, Kana (VerfasserIn)
Weitere Verfasser:	Suzuki, Yoshihiro, Yoshimaru, Tetsuro, Inoue, Toshio, Terui, Tadashi, Ochiai, Toyoko, Ra, Chisei
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2009
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Anti-Inflammatory Agents, Non-Steroidal Calcium Channels, L-Type Salicylates Leukotriene C4 2CU6TT9V48 Immunoglobulin E 37341-29-0 Mitogen-Activated Protein Kinase 3 mehr... EC 2.7.11.24 p38 Mitogen-Activated Protein Kinases Phospholipases A2 EC 3.1.1.4 Aspirin R16CO5Y76E Calcium SY7Q814VUP