Anti-Siglec-F antibody inhibits oral egg allergen induced intestinal eosinophilic inflammation in a mouse model

Siglec-F is a sialic acid binding immunoglobulin-superfamily receptor that is highly expressed on eosinophils. We have used a mouse model of oral egg ovalbumin (OVA)-induced eosinophilic inflammation of the gastro-intestinal mucosa associated with diarrhea and weight loss to determine whether admini...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 1 vom: 16. Apr., Seite 157-69
1. Verfasser: Song, Dae Jin (VerfasserIn)
Weitere Verfasser: Cho, Jae Youn, Miller, Marina, Strangman, Wendy, Zhang, Mai, Varki, Ajit, Broide, David H
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Antibodies Antigens, Differentiation, Myelomonocytic Ccl11 protein, mouse Chemokine CCL11 Sialic Acid Binding Immunoglobulin-like Lectins Siglecf protein, mouse Immunoglobulin E 37341-29-0