Application of electrical impedance equipment in evaluating local lung volume during different PEEP ventilation and at different respiratory rate

OBJECTIVE: To evaluate the applicability of electrical impedance equipment in assessing local lung volume during different PEEP ventilation and at different respiratory rate in neonatal piglets

Bibliographische Detailangaben
Veröffentlicht in:Zhonghua er ke za zhi = Chinese journal of pediatrics. - 1960. - 46(2008), 10 vom: 22. Okt., Seite 779-83
1. Verfasser: Huang, Qi-wei (VerfasserIn)
Weitere Verfasser: Simbruner, Geoge
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Zhonghua er ke za zhi = Chinese journal of pediatrics
Schlagworte:English Abstract Journal Article
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245 1 0 |a Application of electrical impedance equipment in evaluating local lung volume during different PEEP ventilation and at different respiratory rate 
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520 |a OBJECTIVE: To evaluate the applicability of electrical impedance equipment in assessing local lung volume during different PEEP ventilation and at different respiratory rate in neonatal piglets 
520 |a METHODS: Electrical impedance measurements (EIM) were performed on 6 healthy newborn piglets (age 4 +/- 1 d, weight 1.66 +/- 0.31 kg) using 8 electrodes distributed to 4 quadrants of the lung (left, right, upper, lower). Tidal impedance and functional residual impedance changes during PEEP levels of 2, 4, 6 and 8 cm H2O and frequencies ranging from 0.5 to 15 Hz were investigated 
520 |a RESULTS: The sum of regional tidal impedance obtained from four quadrants, significantly reflected tidal volume (VT) measured by a pneumotachograph during both frequency and PEEP changed (r2 = 0.98). A decrease of PEEP 4 to 2 cm H2O caused a significant increase in total tidal impedance (TTI) as well as in VT (P < 0.01 and P < 0.05); whereas an increase in frequency from 0.5 to 15 Hz was associated with a significant decrease in both TTI and VT (P < 0.05 and P < 0.01). Increased frequency had a balancing effect on air distribution, whereas higher PEEP did not result in more homogeneous ventilation. Minimal impedance values (FRI) (surrogate variable for FRC) showed that total FRI significantly decreased with increasing PEEP level 
520 |a CONCLUSIONS: EIM demonstrated good applicability to assess changes in thoracic gas volume. It is highly suggested that this method could be considered and further studied as a non-invasive bedside method to monitor continuously regional lung ventilation of neonates under any mode of mechanical ventilation 
650 4 |a English Abstract 
650 4 |a Journal Article 
700 1 |a Simbruner, Geoge  |e verfasserin  |4 aut 
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