Deficiency of mannose-binding lectin greatly increases antibody response in a mouse model of vaccination
Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, selectively binds distinct chemical patterns, including carbohydrates expressed on Group B streptococcus (GBS). MBL interacts with IgM, resulting in the activation of MBL-associated serine proteases (MASPs), thus is initiati...
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Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 130(2009), 3 vom: 15. März, Seite 264-71
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| 1. Verfasser: |
Guttormsen, Hilde-Kari
(VerfasserIn) |
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| Weitere Verfasser: |
Stuart, Lynda M,
Shi, Lei,
Carroll, Mike C,
Chen, Jianzhu,
Kasper, Dennis L,
Ezekowitz, R Alan B,
Takahashi, Kazue |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2009
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Immunoglobulin G
Mannose-Binding Lectin |
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