Changes in matrix metalloproteinases and their inhibitors during interferon-beta treatment in multiple sclerosis

Matrix metalloproteinases (MMPs) and tissue inhibitors (TIMPs) play a key role in the pathogenesis of multiple sclerosis (MS) and have been proposed as biomarkers of response to therapy. We investigated serum levels of several MMPs and TIMPs in 43 relapsing-remitting MS (RRMS) patients undergoing in...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 130(2009), 2 vom: 11. Feb., Seite 145-50
1. Verfasser: Comabella, Manuel (VerfasserIn)
Weitere Verfasser: Río, Jordi, Espejo, Carmen, Ruiz de Villa, Mamen, Al-Zayat, Hammad, Nos, Carlos, Deisenhammer, Florian, Baranzini, Sergio E, Nonell, Lara, López, Cristina, Julià, Eva, Oksenberg, Jorge R, Montalban, Xavier
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Immunologic Factors Tissue Inhibitor of Metalloproteinase-1 Tissue Inhibitor of Metalloproteinase-2 127497-59-0 Interferon-beta 77238-31-4 Matrix Metalloproteinase 7 mehr... EC 3.4.24.23 Matrix Metalloproteinase 2 EC 3.4.24.24 Matrix Metalloproteinase 9 EC 3.4.24.35