Formation and characterization of fluid lipid bilayers on alumina

Fluid lipid bilayers were deposited on alumina substrates with the use of bubble collapse deposition (BCD). Previous studies using vesicle rupture have required the use of charged lipids or surface functionalization to induce bilayer formation on alumina, but these modifications are not necessary wi...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 24(2008), 22 vom: 18. Nov., Seite 12734-7
1. Verfasser: Mager, Morgan D (VerfasserIn)
Weitere Verfasser: Almquist, Benjamin, Melosh, Nicholas A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Lipid Bilayers Lipids Oxides Phosphatidylcholines Aluminum CPD4NFA903 Aluminum Oxide mehr... LMI26O6933 1-palmitoyl-2-oleoylphosphatidylcholine TE895536Y5
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520 |a Fluid lipid bilayers were deposited on alumina substrates with the use of bubble collapse deposition (BCD). Previous studies using vesicle rupture have required the use of charged lipids or surface functionalization to induce bilayer formation on alumina, but these modifications are not necessary with BCD. Photobleaching experiments reveal that the diffusion coefficient of POPC on alumina is 0.6 microm (2)/s, which is much lower than the 1.4-2.0 microm (2)/s reported on silica. Systematically accounting for roughness, immobile regions and membrane viscosity shows that pinning sites account for about half of this drop in diffusivity. The remainder of the difference is attributed to a more tightly bound water state on the alumina surface, which induces a larger drag on the bilayer 
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650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a Oxides  |2 NLM 
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700 1 |a Almquist, Benjamin  |e verfasserin  |4 aut 
700 1 |a Melosh, Nicholas A  |e verfasserin  |4 aut 
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