Metals and the integrity of a biological coating : the cuticle of mussel byssus

The cuticle of mussel byssal threads is a robust natural coating that combines high extensibility with high stiffness and hardness. In this study, fluorescence microscopy and elemental analysis were exploited to show that the 3,4-dihydroxyphenyl-L-alanine (dopa) residues of mussel foot protein-1 col...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 25(2009), 6 vom: 09. Apr., Seite 3323-6
1. Verfasser: Holten-Andersen, Niels (VerfasserIn)
Weitere Verfasser: Mates, Thomas E, Toprak, Muhammet S, Stucky, Galen D, Zok, Frank W, Waite, J Herbert
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Biocompatible Materials Metals Levodopa 46627O600J Iron E1UOL152H7 Calcium SY7Q814VUP
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520 |a The cuticle of mussel byssal threads is a robust natural coating that combines high extensibility with high stiffness and hardness. In this study, fluorescence microscopy and elemental analysis were exploited to show that the 3,4-dihydroxyphenyl-L-alanine (dopa) residues of mussel foot protein-1 colocalize with Fe and Ca distributions in the cuticle of Mytilus galloprovincialis mussel byssal threads. Chelated removal of Fe and Ca from the cuticle of intact threads resulted in a 50% reduction in cuticle hardness, and thin sections subjected to the same treatment showed a disruption of cuticle integrity. Dopa-metal complexes may provide significant interactions for the integrity of composite cuticles deformed under tension 
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700 1 |a Toprak, Muhammet S  |e verfasserin  |4 aut 
700 1 |a Stucky, Galen D  |e verfasserin  |4 aut 
700 1 |a Zok, Frank W  |e verfasserin  |4 aut 
700 1 |a Waite, J Herbert  |e verfasserin  |4 aut 
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