DNA release dynamics from reducible polyplexes by atomic force microscopy

Controlled intracellular disassembly of polyelectrolyte complexes of polycations and DNA (polyplexes) is a crucial step for the success of nonviral gene delivery. Motivated by our previous observation of different gene delivery performances among multiblock reducible copolypeptide vectors ( Manickam...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 24(2008), 21 vom: 04. Nov., Seite 12474-82
Auteur principal: Wan, Lei (Auteur)
Autres auteurs: Manickam, Devika S, Oupický, David, Mao, Guangzhao
Format: Article en ligne
Langue:English
Publié: 2008
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Peptides Histidine 4QD397987E DNA 9007-49-2