Distinct subsets of regulatory T cells during pregnancy : is the imbalance of these subsets involved in the pathogenesis of preeclampsia?

Regulatory T cells (CD4(+)CD25(+)FoxP3(+)-Treg cells) are important regulators of tolerance induction during pregnancy. We now found that the number of CD4(+)CD25(+)FoxP3(+)-Treg cells decreases during normal course of pregnancy and even more so in women affected by preeclampsia. The functional acti...

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Publié dans:	Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 3 vom: 01. Dez., Seite 401-12
Auteur principal:	Steinborn, Andrea (Auteur)
Autres auteurs:	Haensch, Gertrud M, Mahnke, Karsten, Schmitt, Edgar, Toermer, Anne, Meuer, Stefan, Sohn, Christof
Format:	Article en ligne
Langue:	English
Publié:	2008
Accès à la collection:	Clinical immunology (Orlando, Fla.)
Sujets:	Journal Article Research Support, Non-U.S. Gov't FOXP3 protein, human Forkhead Transcription Factors Interleukin-2 Receptor alpha Subunit