B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer
Myeloid-derived suppressor cells (MDSCs) accumulate in tumor-bearing hosts and are associated with immune suppression. Here, we described high level of expression of B7-H1 (CD274), PD-1 (CD279) and CTLA4 (CD152) by Gr-1(+)CD11b(+) MDSCs obtained from both ascites and spleens of mice bearing the 1D8...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 3 vom: 10. Dez., Seite 471-81
|
1. Verfasser: |
Liu, Yu
(VerfasserIn) |
Weitere Verfasser: |
Zeng, Bin,
Zhang, Zhuohan,
Zhang, Yuan,
Yang, Rongcun |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2008
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Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Antigens, CD
Antigens, Differentiation
B7-1 Antigen
B7-H1 Antigen
CD11b Antigen
CTLA-4 Antigen
Cd274 protein, mouse
Ctla4 protein, mouse
mehr...
Forkhead Transcription Factors
Foxp3 protein, mouse
Membrane Glycoproteins
Pdcd1 protein, mouse
Peptides
Programmed Cell Death 1 Receptor
RNA, Small Interfering |