B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer

Myeloid-derived suppressor cells (MDSCs) accumulate in tumor-bearing hosts and are associated with immune suppression. Here, we described high level of expression of B7-H1 (CD274), PD-1 (CD279) and CTLA4 (CD152) by Gr-1(+)CD11b(+) MDSCs obtained from both ascites and spleens of mice bearing the 1D8...

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Publié dans:	Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 3 vom: 10. Dez., Seite 471-81
Auteur principal:	Liu, Yu (Auteur)
Autres auteurs:	Zeng, Bin, Zhang, Zhuohan, Zhang, Yuan, Yang, Rongcun
Format:	Article en ligne
Langue:	English
Publié:	2008
Accès à la collection:	Clinical immunology (Orlando, Fla.)
Sujets:	Journal Article Research Support, Non-U.S. Gov't Antigens, CD Antigens, Differentiation B7-1 Antigen B7-H1 Antigen CD11b Antigen CTLA-4 Antigen Cd274 protein, mouse Ctla4 protein, mouse plus... Forkhead Transcription Factors Foxp3 protein, mouse Membrane Glycoproteins Pdcd1 protein, mouse Peptides Programmed Cell Death 1 Receptor RNA, Small Interfering