Invariant natural killer T cells and immunotherapy of cancer

Invariant CD1d restricted natural killer T (iNKT) cells are regulatory cells that express a canonical TCR-Valpha-chain (Valpha24.Jalpha18 in humans and Valpha14.Jalpha18 in mice) which recognizes glycolipid antigens presented by the monomorphic CD1d molecule. They can secrete a wide variety of both...

Description complète

Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 2 vom: 15. Nov., Seite 182-94
Auteur principal: Molling, Johan W (Auteur)
Autres auteurs: Moreno, María, van der Vliet, Hans J J, van den Eertwegh, Alfons J M, Scheper, Rik J, von Blomberg, B Mary E, Bontkes, Hetty J
Format: Article en ligne
Langue:English
Publié: 2008
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't Review Antigens, CD1 Antigens, CD1d CD1D protein, human