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231223s2008 xx |||||o 00| ||eng c |
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|a 10.1021/la801497d
|2 doi
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|a pubmed24n0607.xml
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|a (DE-627)NLM182164438
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|a (NLM)18763817
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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1 |
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|a Erickson, Blake
|e verfasserin
|4 aut
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|a Interactions of poly(amidoamine) dendrimers with Survanta lung surfactant
|b the importance of lipid domains
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|c 2008
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 28.10.2008
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|a Date Revised 20.10.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a The interaction of generation 5 (G5) and 7 (G7) poly(amidoamine) (PAMAM) dendrimers with mica-supported Survanta bilayers is studied with atomic force microscopy (AFM). In these experiments, Survanta forms distinct gel and fluid domains with differing lipid composition. Nanoscale defects are induced by the PAMAM dendrimers. The positively charged dendrimers remove lipid from the fluid domains at a significantly greater rate than for the gel domains. Dendrimer accumulation on lipid edges and terraces preceding lipid removal has been directly imaged. Immediately following lipid removal, the mica surface is clean, indicating that lipid defects are not induced by dendrimers binding to the mica substrate and displacing the lipid
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a Research Support, Non-U.S. Gov't
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|a Biological Products
|2 NLM
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|a Dendrimers
|2 NLM
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|a Fatty Acids
|2 NLM
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|a Lipids
|2 NLM
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|a Poly(amidoamine)
|2 NLM
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|a Polyamines
|2 NLM
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| 650 |
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|a Proteins
|2 NLM
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|a Pulmonary Surfactants
|2 NLM
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| 650 |
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|a beractant
|2 NLM
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| 650 |
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|a S866O45PIG
|2 NLM
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|a DiMaggio, Stassi C
|e verfasserin
|4 aut
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|a Mullen, Douglas G
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kelly, Christopher V
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Leroueil, Pascale R
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Berry, Stephanie A
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Baker, James R
|c Jr
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Orr, Bradford G
|e verfasserin
|4 aut
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| 700 |
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|a Banaszak Holl, Mark M
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 24(2008), 19 vom: 07. Okt., Seite 11003-8
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:24
|g year:2008
|g number:19
|g day:07
|g month:10
|g pages:11003-8
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|u http://dx.doi.org/10.1021/la801497d
|3 Volltext
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