Patients suffering from acute graft-versus-host disease after bone-marrow transplantation have functional CD4+CD25hiFoxp3+ regulatory T cells
Acute Graft-Versus-Host Disease (aGVHD), mediated by CD4(+) and CD8(+) effector T cells, is a life-threatening complication in hematopoietic stem cell (HSC) transplantation. Naturally-occurring CD4(+)CD25(hi)(Foxp3(+)) regulatory T cells (T(reg)) have been shown to modulate tolerance to aGVHD in mur...
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Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 2 vom: 19. Nov., Seite 241-8
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| 1. Verfasser: |
Noël, G
(VerfasserIn) |
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| Weitere Verfasser: |
Bruniquel, D,
Birebent, B,
DeGuibert, S,
Grosset, J-M,
Bernard, M,
Dauriac, C,
Chevallier, P,
Lamy-de-la-Chapelle, T,
Semana, G,
Brinster, C |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2008
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
FOXP3 protein, human
Forkhead Transcription Factors
Interleukin-7 Receptor alpha Subunit |
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