IFNalpha treatment generates antigen-presenting cells insensitive to atorvastatin inhibition of MHC-II expression
IFNalpha is an immunostimulatory cytokine involved in the development of autoimmunity. Atorvastatin, a cholesterol-lowering drug, also possess immunomodulatory effects, being able to downregulate IFNgamma-induced MHC-II expression. In this study we evaluated the role of IFNalpha in monocyte differen...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 2 vom: 04. Nov., Seite 350-9 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
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2008
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Heptanoic Acids Histocompatibility Antigens Class II Hydroxymethylglutaryl-CoA Reductase Inhibitors Interferon-alpha Pyrroles Interleukin-4 207137-56-2 Granulocyte-Macrophage Colony-Stimulating Factor mehr... |
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