Dendritic cells loaded with apoptotic oligodendrocytes as a source of myelin T-cell epitopes in multiple sclerosis
Evidence suggests that T-cell response to myelin basic protein (MBP) plays an important role in multiple sclerosis (MS). However, the mechanism of generation for MBP immunogenic epitopes is unclear. A series of specific CD4(+) T-cell lines was obtained by stimulating peripheral blood mononuclear cel...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 2 vom: 13. Nov., Seite 286-94
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| 1. Verfasser: |
Meloni, Francesca
(VerfasserIn) |
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| Weitere Verfasser: |
Accapezzato, Daniele,
Agresti, Cristina,
Aloisi, Francesca,
Ristori, Giovanni,
Salvetti, Marco,
Furlan, Roberto,
Martino, Gianvito,
Barnaba, Vincenzo,
Paroli, Marino |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2008
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Cytokines
Epitopes, T-Lymphocyte
HLA-DR Antigens
Histocompatibility Antigens Class II
Myelin Basic Protein |
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