Fundamental differences in the dynamics of CNS lesion development and composition in MP4- and MOG peptide 35-55-induced experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) is characterized by a dynamic inflammatory process in which CNS lesions of distinct cellular composition coexist. In particular the formation of B cell plaques has been ascribed an important role as predictor of disease progression. Here we show that the novel MBP-PLP fusion...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 2 vom: 15. Nov., Seite 256-67
1. Verfasser: Kuerten, Stefanie (VerfasserIn)
Weitere Verfasser: Javeri, Sita, Tary-Lehmann, Magdalena, Lehmann, Paul V, Angelov, Doychin N
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Glycoproteins MP4 protein, chimeric Myelin Basic Protein Myelin Proteolipid Protein Myelin-Oligodendrocyte Glycoprotein Peptide Fragments Recombinant Fusion Proteins myelin oligodendrocyte glycoprotein (35-55)