Products of anti-CD3/anti-CD28 activated lymphocytes induce differentiation and maturation of dendritic cells and have adjuvant-like activity in vitro and in vivo
Dendritic cells (DC) orchestrate immune responses under direction of cytokines/chemokines in their microenvironment. To investigate the influence of that generated during T cell activation, we stimulated peripheral blood mononuclear cells (PBMC) with anti-CD3 and anti-CD28 coated beads and tested ce...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 1 vom: 15. Okt., Seite 58-68
|
1. Verfasser: |
Harris, Kristina M
(VerfasserIn) |
Weitere Verfasser: |
Lenz, Petra,
Hankey, Kim G,
MacVittie, Thomas,
Farese, Ann,
Nakajima, Kaori,
Hasumi, Kenichiro,
Mann, Dean L |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2008
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Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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Schlagworte: | Journal Article
Adjuvants, Immunologic
Antibodies
CD28 Antigens
CD3 Complex
CPG-oligonucleotide
Culture Media, Conditioned
Cytokines
Oligodeoxyribonucleotides
Vaccines |