Products of anti-CD3/anti-CD28 activated lymphocytes induce differentiation and maturation of dendritic cells and have adjuvant-like activity in vitro and in vivo

Dendritic cells (DC) orchestrate immune responses under direction of cytokines/chemokines in their microenvironment. To investigate the influence of that generated during T cell activation, we stimulated peripheral blood mononuclear cells (PBMC) with anti-CD3 and anti-CD28 coated beads and tested ce...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 1 vom: 15. Okt., Seite 58-68
1. Verfasser: Harris, Kristina M (VerfasserIn)
Weitere Verfasser: Lenz, Petra, Hankey, Kim G, MacVittie, Thomas, Farese, Ann, Nakajima, Kaori, Hasumi, Kenichiro, Mann, Dean L
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Adjuvants, Immunologic Antibodies CD28 Antigens CD3 Complex CPG-oligonucleotide Culture Media, Conditioned Cytokines Oligodeoxyribonucleotides Vaccines