|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM181438836 |
| 003 |
DE-627 |
| 005 |
20231223161243.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231223s2008 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1021/la801472x
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0605.xml
|
| 035 |
|
|
|a (DE-627)NLM181438836
|
| 035 |
|
|
|a (NLM)18686981
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Filippov, Sergey
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Novel pH-responsive nanoparticles
|
| 264 |
|
1 |
|c 2008
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 13.11.2008
|
| 500 |
|
|
|a Date Revised 01.12.2018
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a In this work we report a new type of pH-responsive micelle-like nanoparticle. Reversible nanoscale structures are formed in solutions of a pH-sensitive hydrophobic polyelectrolyte, poly( N-methacryloyl- l-valine) or poly( N-methacryloyl- l-phenylalanine), and nonionic surfactant (Brij 98) in the presence of hydrochloric acid. The influence of composition and pH on particles size and shape was investigated by a variety of methods. An entity's size and polydispersity could be varied in a broad range making them a perspective candidate as a drug carrier. Unlike the case of typical micelles, our results indicate the presence of cavities in the formed particles. A hypothetical model of a nanoparticle and mechanism of formation are proposed
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
7 |
|a Electrolytes
|2 NLM
|
| 650 |
|
7 |
|a Ions
|2 NLM
|
| 650 |
|
7 |
|a Micelles
|2 NLM
|
| 650 |
|
7 |
|a Plant Oils
|2 NLM
|
| 650 |
|
7 |
|a Polymers
|2 NLM
|
| 650 |
|
7 |
|a Polyethylene Glycols
|2 NLM
|
| 650 |
|
7 |
|a 3WJQ0SDW1A
|2 NLM
|
| 650 |
|
7 |
|a Phenylalanine
|2 NLM
|
| 650 |
|
7 |
|a 47E5O17Y3R
|2 NLM
|
| 650 |
|
7 |
|a polyethylene glycol oleyl ether
|2 NLM
|
| 650 |
|
7 |
|a 9004-98-2
|2 NLM
|
| 650 |
|
7 |
|a Valine
|2 NLM
|
| 650 |
|
7 |
|a HG18B9YRS7
|2 NLM
|
| 700 |
1 |
|
|a Hrubý, Martin
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Konák, Cestmír
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Macková, Hana
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Spírková, Milena
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Stepánek, Petr
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 24(2008), 17 vom: 02. Sept., Seite 9295-301
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
|
| 773 |
1 |
8 |
|g volume:24
|g year:2008
|g number:17
|g day:02
|g month:09
|g pages:9295-301
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1021/la801472x
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_22
|
| 912 |
|
|
|a GBV_ILN_350
|
| 912 |
|
|
|a GBV_ILN_721
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 24
|j 2008
|e 17
|b 02
|c 09
|h 9295-301
|