Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice
Type 1 diabetes (T1D) is characterized by the T cell mediated destruction of the insulin-producing beta cells. Antigen-specific immunotherapies are used to selectively tolerize beta cell-specific pathogenic T cells either directly, or indirectly through the induction of immunoregulatory T cells. A k...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 129(2008), 1 vom: 01. Okt., Seite 49-57 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
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2008
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Autoantigens Immunoglobulin Fc Fragments Recombinant Fusion Proteins Vaccines, DNA Interleukin-4 207137-56-2 Glutamate Decarboxylase EC 4.1.1.15 glutamate decarboxylase 2 |
| Online verfügbar |
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