Physical state of poorly water soluble therapeutic molecules loaded into SBA-15 ordered mesoporous silica carriers : a case study with itraconazole and ibuprofen

The ordered mesoporous silica material SBA-15 was loaded with the model drugs itraconazole and ibuprofen using three different procedures: (i) adsorption from solution, (ii) incipient wetness impregnation, and (iii) heating of a mixture of drug and SBA-15 powder. The location of the drug molecules i...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 24(2008), 16 vom: 19. Aug., Seite 8651-9
1. Verfasser: Mellaerts, Randy (VerfasserIn)
Weitere Verfasser: Jammaer, Jasper A G, Van Speybroeck, Michiel, Chen, Hong, Van Humbeeck, Jan, Augustijns, Patrick, Van den Mooter, Guy, Martens, Johan A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article SBA-15 Water 059QF0KO0R Itraconazole 304NUG5GF4 Silicon Dioxide 7631-86-9 Ibuprofen WK2XYI10QM