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231223s2008 xx |||||o 00| ||eng c |
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|a 10.1021/la801083h
|2 doi
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|a pubmed25n0603.xml
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|a (DE-627)NLM180905155
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|a (NLM)18627190
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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1 |
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|a Shahgaldian, Patrick
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Amino-substituted amphiphilic calixarenes
|b self-assembly and interactions with DNA
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|c 2008
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 17.09.2008
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|a Date Revised 13.08.2008
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a The amphiphilic 5,11,17,23-tetramino-25,26,27,28-tetradodecyloxycalix[4]arene is shown to self-assemble as stable and well-defined Langmuir monolayers at the air-water interface. The effect of the presence of DNA in the subphase reveals interactions taking place at the interface between the positively charged surface and the negatively charged DNA, causing an expansion of the monolayers and a phase transition from a liquid-condensed to a liquid-expanded phase; a slight decrease in the stability of the monolayers is also observed. The title compound is shown to self-assemble, with the absence of a cosurfactant, as stable colloidal suspensions. Photon correlation spectroscopy, zeta-potential measurements, and atomic force microscopy reveal that these colloidal suspensions present a monodisperse size distribution and are composed of positively charged solid lipid nanoparticles (SLNs), with an average hydrodynamic diameter of 190 nm and a surface potential of +13.2 mV. The interaction of these SLNs with double-stranded DNA is demonstrated
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Amines
|2 NLM
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|a Lipids
|2 NLM
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|a Calixarenes
|2 NLM
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|a 130036-26-9
|2 NLM
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|a DNA
|2 NLM
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|a 9007-49-2
|2 NLM
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| 700 |
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|a Sciotti, Michel A
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Pieles, Uwe
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1991
|g 24(2008), 16 vom: 19. Aug., Seite 8522-6
|w (DE-627)NLM098181009
|x 0743-7463
|7 nnns
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| 773 |
1 |
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|g volume:24
|g year:2008
|g number:16
|g day:19
|g month:08
|g pages:8522-6
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| 856 |
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|u http://dx.doi.org/10.1021/la801083h
|3 Volltext
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