Poly(dG) spacers lead to increased surface coverage of DNA probes : an XPS study of oligonucleotide binding to zirconium phosphonate modified surfaces

A spacer is often employed between the surface linking group and the probe sequence to improve the performance of DNA microarrays. Previous work demonstrated that a consecutive stretch of guanines as a spacer increased target capture during hybridization relative to probes with either no spacer or a...

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Publié dans:	Langmuir : the ACS journal of surfaces and colloids. - 1985. - 24(2008), 14 vom: 15. Juli, Seite 7394-9
Auteur principal:	Lane, Sarah M (Auteur)
Autres auteurs:	Monot, Julien, Petit, Marc, Tellier, Charles, Bujoli, Bruno, Talham, Daniel R
Format:	Article en ligne
Langue:	English
Publié:	2008
Accès à la collection:	Langmuir : the ACS journal of surfaces and colloids
Sujets:	Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. DNA Probes Oligonucleotides zirconium phosphate 13765-95-2 Poly G 25191-14-4 poly(dG) plus... 25656-92-2 Zirconium C6V6S92N3C