Magnetoresponsive squalenoyl gemcitabine composite nanoparticles for cancer active targeting

Gemcitabine is widely used against a variety of solid tumors; however, it possesses some important drawbacks such as rapid deamination leading to short biological half-life and induction of tumor resistance. We have shown previously that the covalent coupling of squalene (a precursor of cholesterol...

Description complète

Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 24(2008), 14 vom: 15. Juli, Seite 7512-9
Auteur principal: Arias, José L (Auteur)
Autres auteurs: Reddy, L Harivardhan, Couvreur, Patrick
Format: Article en ligne
Langue:English
Publié: 2008
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Deoxycytidine 0W860991D6 Squalene 7QWM220FJH Gemcitabine