Distribution of IgM and IgG antibodies to oxidized LDL in immune complexes isolated from patients with type 1 diabetes and its relationship with nephropathy

Distribution of IgM and IgG antibodies to oxidized LDL in immune complexes isolated from patients with type 1 diabetes and its relationship with nephropathy

Modified lipoproteins are immunogenic and play a key pathogenic role in vascular disease. Antibodies to oxidized LDL (oxLDL) are mostly of the pro-inflammatory IgG1 and IgG3 isotypes. We measured IgG and IgM oxLDL antibodies in immune complexes (IC) isolated from 36 patients with type 1 diabetes usi...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 127(2008), 3 vom: 01. Juni, Seite 394-400
1. Verfasser: Virella, Gabriel (VerfasserIn)
Weitere Verfasser: Carter, Rickey E, Saad, Antonio, Crosswell, Edward G, Game, B Andrew, DCCT/EDIC Study Group, Lopes-Virella, Maria F
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Antigen-Antibody Complex Autoantibodies Immunoglobulin G Immunoglobulin M Lipoproteins, LDL oxidized low density lipoprotein