Fiber-modified recombinant adenoviral constructs encoding hepatitis C virus proteins induce potent HCV-specific T cell response

Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes (CTLs) play an important role in HCV clearance. The frequency of HCV-specific T(CD8) in peripheral blood of HCV-infected donors is very low and HCV cannot be cultivated for reinfection of antigen presenting cells, making it difficult to detect...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 128(2008), 3 vom: 15. Sept., Seite 329-39
1. Verfasser: Thammanichanond, Duangtawan (VerfasserIn)
Weitere Verfasser: Moneer, Sarah, Yotnda, Patricia, Aitken, Campbell, Earnest-Silveira, Linda, Jackson, David, Hellard, Margaret, McCluskey, James, Torresi, Joseph, Bharadwaj, Mandvi
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Capsid Proteins Cytokines Hepatitis C Antigens Viral Hepatitis Vaccines hexon capsid protein, Adenovirus