SURF imaging : in vivo demonstration of an ultrasound contrast agent detection technique
A dual-band method for ultrasound contrast agent detection is demonstrated in vivo in an animal experiment using pigs. The method is named Second -order UltRasound Field Imaging, abbreviated SURF Imaging. It relies on simultaneously transmitting two ultrasound pulses with a large separation in frequ...
| Publié dans: | IEEE transactions on ultrasonics, ferroelectrics, and frequency control. - 1986. - 55(2008), 5 vom: 01. Mai, Seite 1112-21 |
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| Auteur principal: | |
| Autres auteurs: | , , , , |
| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2008
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| Accès à la collection: | IEEE transactions on ultrasonics, ferroelectrics, and frequency control |
| Sujets: | Evaluation Study Journal Article Research Support, Non-U.S. Gov't Contrast Media Phospholipids contrast agent BR1 Sulfur Hexafluoride WS7LR3I1D6 |
| Résumé: | A dual-band method for ultrasound contrast agent detection is demonstrated in vivo in an animal experiment using pigs. The method is named Second -order UltRasound Field Imaging, abbreviated SURF Imaging. It relies on simultaneously transmitting two ultrasound pulses with a large separation in frequency. Here, a low-frequency pulse of 0.9 MHz is combined with a high-frequency pulse of 7.5 MHz. The low-frequency pulse is used to manipulate the properties of the contrast agent, and the high frequency pulse is used for high-resolution contrast detection and imaging. An annular array capable of transmitting the low- and high-frequency pulses simultaneously was constructed and fitted to a mechanically scanned probe used in a GE Vingmed System 5 ultrasound scanner. The scanner was modified and adapted for the dual-band transmit technique. In-house software was written for post-processing of recorded IQ-data. Contrast-processed B-mode images of pig kidneys after bolus injections of 1 mL of Sonovuer are presented. The images display contrast detection with contrast-to-tissue ratios ranging from 15-40 dB. The results demonstrate the potential of SURF Imaging as an ultrasound contrast detection technique for clinically high ultrasound frequencies. This may allow ultrasound contrast imaging to be available for a wide range of applications |
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| Description: | Date Completed 08.07.2008 Date Revised 10.12.2019 published: Print Citation Status MEDLINE |
| ISSN: | 1525-8955 |
| DOI: | 10.1109/TUFFC.2008.763 |