Full-term delivery following intracytoplasmic sperm injection in a case of male hypogonadotropic hypogonadism after 8-year treatment with HCG and HMG

A 19-year-old male, who had undergone bilateral orchiopexy at 5 years of age in the Department of Pediatric Surgery, was referred to our clinic presenting with bilateral small testes. Bilateral testis volume was 4 ml involving a small penis and scant pubic hair per Tanner Stage 2. Serum luteinizing...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 54(2008), 4 vom: 30. Apr., Seite 313-6
1. Verfasser: Amano, Toshiyasu (VerfasserIn)
Weitere Verfasser: Imao, Tetsuya, Takemae, Katsuro, Mizusawa, Hiroya, Miura, Hideho
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Case Reports English Abstract Journal Article Chorionic Gonadotropin Menotropins 61489-71-2
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520 |a A 19-year-old male, who had undergone bilateral orchiopexy at 5 years of age in the Department of Pediatric Surgery, was referred to our clinic presenting with bilateral small testes. Bilateral testis volume was 4 ml involving a small penis and scant pubic hair per Tanner Stage 2. Serum luteinizing hormone, follicle stimulating hormone and testosterone levels were low. Results of hormonal loading tests, including luteinizing hormone-releasing hormone (LH-RH) and human chorionic gonadotropin (HCG), were positive. Brain computed tomographic scan revealed no abnormal findings. The diagnosis of male hypogonadotropic hypogonadism was rendered based on these data. Administration of LH-RH for 1 year was ineffective. Subsequently, HCG and human menopausal gonadotropin (HMG) treatments were initiated. The symptoms of male insufficiency improved; moreover, sperm formation was apparent following HCG and HMG treatments. The patient has received HCG and HMG injections for eight years; furthermore, his wife delivered a boy consequent to the first intracytoplasmic sperm injection 
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