Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse
Systemic lupus erythematosus (SLE) occurs nine times more often in females than males. The purpose of this study was to determine the impact of estrogen receptor (ER) null genotypes on disease in lupus prone NZM2410 (NZM) and MRL/lpr mice, as a method to define the role of estrogen receptor signalin...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 128(2008), 2 vom: 31. Aug., Seite 259-68
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| 1. Verfasser: |
Svenson, John L
(VerfasserIn) |
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| Weitere Verfasser: |
EuDaly, Jackie,
Ruiz, Phil,
Korach, Kenneth S,
Gilkeson, Gary S |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2008
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Autoantibodies
Estrogen Receptor alpha
Estrogen Receptor beta |
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