An affinity-based strategy for the design of selective displacers for the chromatographic separation of proteins

We describe an affinity-based strategy for designing selective protein displacers for the chromatographic purification of proteins. To design a displacer that is selective for a target protein, we attached a component with affinity for the target protein to a resin-binding component; we then tested...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 24(2008), 13 vom: 01. Juni, Seite 6768-73
1. Verfasser: Vutukuru, Srinavya (VerfasserIn)
Weitere Verfasser: Kate, Sandesh D, McCallum, Scott A, Morrison, Christopher J, Cramer, Steven M, Kane, Ravi S
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Proteins Avidin 1405-69-2 Biotin 6SO6U10H04 Aprotinin 9087-70-1 Muramidase EC 3.2.1.17