CD16+ gammadelta T cells mediate antibody dependent cellular cytotoxicity : potential mechanism in the pathogenesis of multiple sclerosis

Our overall objective is to understand the role of gammadelta T cells in the pathogenesis of the central nervous system (CNS) autoimmune disease multiple sclerosis (MS). We have demonstrated that gammadelta T cells are directly cytotoxic to CNS cells in vitro. Although the exact mechanism of damage...

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Bibliographische Detailangaben

Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 128(2008), 2 vom: 01. Aug., Seite 219-27
1. Verfasser:	Chen, Zhihong (VerfasserIn)
Weitere Verfasser:	Freedman, Mark S
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2008
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Antibodies, Monoclonal Antibodies, Monoclonal, Murine-Derived Antigens, CD20 Antineoplastic Agents Receptors, Antigen, T-Cell, gamma-delta Receptors, IgG Rituximab 4F4X42SYQ6