Synovial VLA-1+ T cells display an oligoclonal and partly distinct repertoire in rheumatoid and psoriatic arthritis

VLA-1 integrin expressing T cells are more frequent in inflammatory synovial fluids (SF) compared to peripheral blood. Recent studies suggest that VLA-1 expression mainly marks IFNgamma+ T cells while excluding both IL-4+ and regulatory FoxP3+ T cells. To further characterize the TCR repertoire of t...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 128(2008), 1 vom: 15. Juli, Seite 75-84
1. Verfasser: Goldstein, Itamar (VerfasserIn)
Weitere Verfasser: Simon, Amos J, Ben Horin, Shomron, Matzri, Sarit, Koltakov, Alexander, Langevitz, Pnina, Rechavi, Gideon, Amariglio, Ninette, Bank, Ilan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Complementarity Determining Regions Integrin alpha1beta1 Receptors, Antigen, T-Cell, alpha-beta