Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation

CD4+ T cells specific for the diabetes-associated autoantigen GAD65 were analyzed using peripheral blood samples after pancreas transplantation in subjects with T1D with clinical evidence of recurrent autoimmune diabetes. MHC class II tetramers facilitated the identification and cloning of antigen-s...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 128(2008), 1 vom: 15. Juli, Seite 23-30
Auteur principal: Laughlin, Elsa (Auteur)
Autres auteurs: Burke, George, Pugliese, Alberto, Falk, Ben, Nepom, Gerald
Format: Article en ligne
Langue:English
Publié: 2008
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Autoantigens Epitopes, T-Lymphocyte HLA-DR4 Antigen Immunosuppressive Agents Receptors, Antigen, T-Cell Glutamate Decarboxylase EC 4.1.1.15 glutamate decarboxylase 2