Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation
CD4+ T cells specific for the diabetes-associated autoantigen GAD65 were analyzed using peripheral blood samples after pancreas transplantation in subjects with T1D with clinical evidence of recurrent autoimmune diabetes. MHC class II tetramers facilitated the identification and cloning of antigen-s...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 128(2008), 1 vom: 15. Juli, Seite 23-30
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| 1. Verfasser: |
Laughlin, Elsa
(VerfasserIn) |
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| Weitere Verfasser: |
Burke, George,
Pugliese, Alberto,
Falk, Ben,
Nepom, Gerald |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2008
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Autoantigens
Epitopes, T-Lymphocyte
HLA-DR4 Antigen
Immunosuppressive Agents
Receptors, Antigen, T-Cell
Glutamate Decarboxylase
EC 4.1.1.15
glutamate decarboxylase 2 |
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