Investigation of the mechanism of beta-amyloid fibril formation by kinetic and thermodynamic analyses

Extracellular beta-amyloid (A beta) deposit is considered as one of the primary factors that induce Alzheimer's disease (AD). The effects of various environmental factors, including temperature, ionic strength, and pH, on A beta (1-40) aggregation mechanisms were investigated in this study by s...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 24(2008), 11 vom: 03. Juni, Seite 5802-8
1. Verfasser: Lin, Ming-Shen (VerfasserIn)
Weitere Verfasser: Chen, Liang-Yu, Tsai, Hui-Ting, Wang, Steven S-S, Chang, Yung, Higuchi, Akon, Chen, Wen-Yih
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Amyloid Amyloid beta-Peptides Peptide Fragments amyloid beta-protein (1-40)