A case of prostatic duct adenocarcinoma : its clinical significance in comparison with typical acinar adenocarcinoma

We report a case of prostatic duct adenocarcinoma treated with radical prostatectomy. Advanced pathological stage (pT3bpN1) was beyond the prediction of the favorable preoperative parameters (cT1cN0, PSA 7.64 ng/ml). The main tumor of ductal adenocarcinoma was occupying the transitional zone and sur...

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Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 54(2008), 3 vom: 15. März, Seite 243-7
1. Verfasser: Takazawa, Ryoji (VerfasserIn)
Weitere Verfasser: Kawakami, Satoru, Yamamoto, Kohei, Kubo, Yuichi, Kageyama, Yukio, Kihara, Kazunori
Format: Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Case Reports Comparative Study Journal Article
Beschreibung
Zusammenfassung:We report a case of prostatic duct adenocarcinoma treated with radical prostatectomy. Advanced pathological stage (pT3bpN1) was beyond the prediction of the favorable preoperative parameters (cT1cN0, PSA 7.64 ng/ml). The main tumor of ductal adenocarcinoma was occupying the transitional zone and surrounded by scattered micro-foci of acinar adenocarcinoma. We identified coexistence of ductal and acinar adenocarcinoma cells side by side in the same gland. Pure ductal cancer cells were detected in the metastasized lymph node without acinar cancer cells. Strong staining of PSA and loss of p63 expression by both types of adenocarcinoma cells were confirmed immunohistochemically. We discuss the clinical significance of prostatic duct adenocarcinoma in comparision with typical acinar adenocarcinoma
Beschreibung:Date Completed 13.05.2008
Date Revised 16.04.2008
published: Print
Citation Status MEDLINE
ISSN:0018-1994