Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus : implications for Th17-mediated inflammation in auto-immunity

IL-23-dependent IL-17-producing T helper (Th) lymphocytes are associated with autoimmunity. We investigated the immunopathological mechanisms for activation of Th17 cells of patients with systemic lupus erythematosus (SLE). Concentration of cytokines/chemokine in plasma and culture supernatant from...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 127(2008), 3 vom: 01. Juni, Seite 385-93
1. Verfasser: Wong, Chun Kwok (VerfasserIn)
Weitere Verfasser: Lit, Lydia Choi Wan, Tam, Lai Shan, Li, Edmund Kwok Ming, Wong, Purple Tsz Yan, Lam, Christopher Wai Kei
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Chemokine CXCL10 Interleukin-17 Interleukin-23 Interleukin-12 187348-17-0