X-ray structure analysis of free-standing lipid membranes facilitated by micromachined apertures

Silicon and Teflon substrates have been structured by wet etching and a focused ion beam (FIB) to obtain very defined, clean apertures. Planar, free-standing lipid membranes (black lipid membranes (BLM)) with enhanced long-term stability have been prepared on these apertures by the methods of Montal...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 24(2008), 9 vom: 06. Mai, Seite 4952-8
1. Verfasser: Beerlink, André (VerfasserIn)
Weitere Verfasser: Wilbrandt, P-J, Ziegler, E, Carbone, D, Metzger, T H, Salditt, Tim
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Ions Lipids Polytetrafluoroethylene 9002-84-0 Silicon Z4152N8IUI
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245 1 0 |a X-ray structure analysis of free-standing lipid membranes facilitated by micromachined apertures 
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520 |a Silicon and Teflon substrates have been structured by wet etching and a focused ion beam (FIB) to obtain very defined, clean apertures. Planar, free-standing lipid membranes (black lipid membranes (BLM)) with enhanced long-term stability have been prepared on these apertures by the methods of Montal and Müller(1,2) as well as Müller and Rudin.(3) The stability and geometric control enables the use of X-ray analysis of free-standing single bilayers. With the presented setup, simultaneous structural and electrophysiological measurements will become feasible 
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700 1 |a Wilbrandt, P-J  |e verfasserin  |4 aut 
700 1 |a Ziegler, E  |e verfasserin  |4 aut 
700 1 |a Carbone, D  |e verfasserin  |4 aut 
700 1 |a Metzger, T H  |e verfasserin  |4 aut 
700 1 |a Salditt, Tim  |e verfasserin  |4 aut 
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