Tumor associated antigen and interleukin-12 mRNA transfected dendritic cells enhance effector function of natural killer cells and antigen specific T-cells

Immunotherapy aiming at the combined activation of tumor associated antigen (TAA) specific cytotoxic T lymphocytes (CTL) and Natural Killer (NK) cells may be crucial to eradicate both MHC-I positive and negative tumors. Vaccination with mature dendritic cells (DC) transfected with mRNA encoding for...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 127(2008), 3 vom: 01. Juni, Seite 375-84
1. Verfasser:	Bontkes, Hetty J (VerfasserIn)
Weitere Verfasser:	Kramer, Duco, Ruizendaal, Janneke J, Meijer, Chris J L M, Hooijberg, Erik
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2008
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Antigens, Neoplasm Cytokines Interleukin-18 RNA, Messenger Receptors, Cytokine Interleukin-12 187348-17-0