Human monocytes represent a competitive source of interferon-alpha in peripheral blood

Interferon-alpha (IFN-alpha) has a critical role in antiviral immunity and plasmacytoid dendritic cells (pDCs) have been demonstrated as the principal IFN-alpha source after Toll-like receptor (TLR) 7 and 9 stimulation. Little is known about the contribution of pDC-independent IFN-alpha sources to t...

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Détails bibliographiques
Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 127(2008), 2 vom: 30. Mai, Seite 252-64
Auteur principal: Hansmann, Leo (Auteur)
Autres auteurs: Groeger, Sabine, von Wulffen, Werner, Bein, Gregor, Hackstein, Holger
Format: Article en ligne
Langue:English
Publié: 2008
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't CpG ODN 2006 Fatty Acids, Monounsaturated Fluorescent Dyes Imidazoles Interferon-alpha Lipopolysaccharide Receptors Oligodeoxyribonucleotides Quaternary Ammonium Compounds plus... TLR7 protein, human Toll-Like Receptor 7 1,2-dioleoyloxy-3-(trimethylammonium)propane MR86K0XRQP Poly I-C O84C90HH2L resiquimod V3DMU7PVXF