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231223s2008 xx |||||o 00| ||eng c |
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|a 10.1002/mrc.2194
|2 doi
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|a pubmed25n0593.xml
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|a (NLM)18297742
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Tao, Yiwen
|e verfasserin
|4 aut
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|a 1H and 13C NMR assignments of three nitrogen containing compounds from the mangrove endophytic fungus (ZZF08)
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|c 2008
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 20.05.2008
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|a Date Revised 08.04.2008
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|a published: Print
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|a Citation Status MEDLINE
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|a 2008 John Wiley & Sons, Ltd.
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|a A new natural product, named phomopsin A, 1-(meta-hydroxyphenyl)-4-hydroxy-3-isoquinolone (1), together with two known compounds cytochalasin H (2) and glucosylceramide (3), was isolated from the mangrove endophytic fungus Phomopsis sp. (ZZF08) obtained from the South China Sea coast. The structures were elucidated by 1D and 2D NMR experiments including COSY, HMQC, and HMBC. According to NMR and single-crystal X-ray diffraction, it was found that some assignments about (1)H and (13)C NMR data for cytochalasin H (2) were probably uncorrected in the previous reports. In our cytotoxicity assays, compound 1 showed moderate cytotoxicity toward KB cells with IC(50) at 28.0 microg ml(-1) and KBv200 cells with IC(50) at 16.8 microg ml(-1), and compound 2 exhibited strong cytotoxicity toward KB cells and KBv200 cells with IC(50) less than 1.25 microg ml(-1)
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Carbon Radioisotopes
|2 NLM
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|a Nitrogen Compounds
|2 NLM
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|a Protons
|2 NLM
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|a Zeng, Xianjian
|e verfasserin
|4 aut
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|a Mou, Chengbo
|e verfasserin
|4 aut
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|a Li, Jun
|e verfasserin
|4 aut
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|a Cai, Xiaoling
|e verfasserin
|4 aut
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|a She, Zhigang
|e verfasserin
|4 aut
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|a Zhou, Shining
|e verfasserin
|4 aut
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|a Lin, Yongcheng
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Magnetic resonance in chemistry : MRC
|d 1985
|g 46(2008), 5 vom: 05. Mai, Seite 501-5
|w (DE-627)NLM098179667
|x 1097-458X
|7 nnns
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| 773 |
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|g volume:46
|g year:2008
|g number:5
|g day:05
|g month:05
|g pages:501-5
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|u http://dx.doi.org/10.1002/mrc.2194
|3 Volltext
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