LPS reduces HIV-1 replication in primary human macrophages partly through an endogenous production of type I interferons

It has been proposed that the systemic immune activation state seen in HIV-1-infected patients is caused by circulating microbial products such as lipopolysaccharide (LPS). Given that macrophages play a key role in HIV-1 pathogenesis, we investigated the LPS-mediated effect on HIV-1 replication in c...

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Bibliographische Detailangaben

Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 127(2008), 2 vom: 15. Mai, Seite 198-205
1. Verfasser:	Simard, Sébastien (VerfasserIn)
Weitere Verfasser:	Maurais, Emilie, Gilbert, Caroline, Tremblay, Michel J
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2008
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Interferon Type I Lipopolysaccharide Receptors Lipopolysaccharides NF-kappa B Receptors, HIV Viral Proteins B18R protein, Vaccinia virus 135847-80-2 mehr... Green Fluorescent Proteins 147336-22-9