Molecular targeting therapy for bladder cancer
Molecular-targeted drugs are agents that act on molecules which are specifically expressed in cancer, or on molecules whose expression is increased in cancer compared to normal tissue, and suppress the growth, infiltration and metastasis of cancer while affecting normal tissue as little as possible...
| Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 54(2008), 1 vom: 08. Jan., Seite 67-75 |
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| Format: | Aufsatz |
| Sprache: | Japanese |
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2008
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| Zugriff auf das übergeordnete Werk: | Hinyokika kiyo. Acta urologica Japonica |
| Schlagworte: | Journal Article Review Antibodies, Monoclonal Retinoblastoma Protein EGFR protein, human EC 2.7.10.1 ErbB Receptors Protein-Tyrosine Kinases |
| Zusammenfassung: | Molecular-targeted drugs are agents that act on molecules which are specifically expressed in cancer, or on molecules whose expression is increased in cancer compared to normal tissue, and suppress the growth, infiltration and metastasis of cancer while affecting normal tissue as little as possible by selectively impairing function in cancer tissue. The major molecular targets in cancer therapy include oncogene products, growth factors and their receptors, signal-transducing molecules, hormone receptors, cell cycle-related proteins, telomerase-related molecules, apoptosis-related molecules, angiogenesis-related molecules, anticancer drug resistance/sensitivity factors, transcription factors, and molecules related to infiltration and metastasis. This paper reports on the molecular-targeted drugs currently considered for bladder cancer |
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| Beschreibung: | Date Completed 01.04.2008 Date Revised 01.12.2018 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |