Enhancement of experimental Graves' disease by intranasal administration of a T cell epitope of the thyrotropin receptor

We previously showed that immunization of mice with murine fibroblasts transfected with the thyrotropin receptor (TSHR) and a murine major histocompatibility complex (MHC) class II molecule induces immune thyroid disease with the humoral and histological features of human Graves' disease in abo...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 127(2008), 1 vom: 01. Apr., Seite 7-13
1. Verfasser: Arima, Takayasu (VerfasserIn)
Weitere Verfasser: Shimojo, Naoki, Yamaguchi, Ken-Ichi, Tomiita, Minako, Kohn, Leonard D, Kohno, Yoichi
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2008
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Cytokines Epitopes, T-Lymphocyte Histocompatibility Antigens Class II Peptides Receptors, Thyrotropin