Self-assembled monolayers of an oligo(ethylene oxide) disulfide and its corresponding thiol assembled from water : characterization and protein resistance

Self-assembled monolayers (SAMs) of the disulfide [S(CH2CH2O)6CH3]2 ([S(EO)6]2) on Au from 95% ethanol and from 100% water are described. Spectroscopic ellipsometry and reflection-absorption infrared spectroscopy indicate that the [S(EO)6]2 films are similar to the disordered films of HS(CH2CH2O)6CH...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 24(2008), 3 vom: 05. Feb., Seite 826-9
Auteur principal: Vanderah, David J (Auteur)
Autres auteurs: Walker, Marlon L, Rocco, Mark A, Rubinson, Kenneth A
Format: Article en ligne
Langue:English
Publié: 2008
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, U.S. Gov't, Non-P.H.S. Biocompatible Materials Proteins Sulfhydryl Compounds Water 059QF0KO0R Serum Albumin, Bovine 27432CM55Q Ethylene Oxide JJH7GNN18P
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520 |a Self-assembled monolayers (SAMs) of the disulfide [S(CH2CH2O)6CH3]2 ([S(EO)6]2) on Au from 95% ethanol and from 100% water are described. Spectroscopic ellipsometry and reflection-absorption infrared spectroscopy indicate that the [S(EO)6]2 films are similar to the disordered films of HS(CH2CH2O)6CH3 ((EO)6) and HS(CH2)3O(CH2CH2O)5CH3 (C3EO5) at their protein adsorption minima. The [S(EO)6]2 SAMs exhibit constant film thickness (d) of 1.2 +/- 0.2 nm over long immersion times (up to 20 days) and do not attain the highly ordered, 7/2 helical structure of the (EO)6 and C3EO5 SAMs (d = 2.0 nm). Exposure of these self-limiting [S(EO)6]2 SAMs to bovine serum albumin show high resistance to protein adsorption 
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700 1 |a Rubinson, Kenneth A  |e verfasserin  |4 aut 
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